1. Spend the money for a good face mask / ventilator.
2. Keep an eye on your temperature control. Don't let it get too hot.
3. This may seem obvious, but keep your face away from the pot. A bead of sweat could make for a bad day.
4. Make sure the kids and the wife are "trained" to leave you alone when you are pouring.
5. Make sure you're only pouring into molds that have hooks or keepers in them.
6. Another obvious one...when dipping bad hook pours, use needle nose pliers, not your fingers. I also keep a dry cotton rag available to wipe down the hook. (Reminds me of a joke which will probably not make it past the joke police...Here goes...what do the starship Enterprise and toilet paper have in common? Answer...they both go around Uranus and are there to wipe out Klingons.).
7. If you are using a Lee Production Pot, make sure to have something within arms reach to catch the hot lead should the pouring rod get stuck in the open position. That's why it's important to maintain your equipment, use flux or a small ball of candle wax, etc.
8. Keep that bucket of water available, just in case.