I typically do not use eyes on most (95+%) of my baits, but my one major exception is when the bite is tough in clear water applications... here I will use the Wutz-it in various sizes (for muskies, small mouth or trout) with a set of lookers, and I am convinced the added realism of having eyes does make a difference on getting bit over using the same color scheme without eyes.
As far as the newer eye shapes, I am already imagining them used in alternate ways to create baits that appear to be smiling, shrugging, winking, or exhibiting other emotions/ moods.