I considered straight fluoro on my mono rods, but the stuff sinks, and I never know when I may need to switch to a float which makes doing so with fluor a giant pain the backside. I tie directly to my braid, jig or, say, Rippin Rapa.
For braid in warmer weather/open water I use Suffix 6 pound with a 2 pound diameter, in white which seems to disappear in the water. Later on in the late fall when I fish marina and harbor dock pilings I use a couple dedicated rods spooled with 3 pound Clam Frost braid in the white. I've never seen the need for a fluoro leader so the knots there don't become an issue for me but those bobber stop knots are a super pain. All types of stops with the tiny eyes are a pain and some just don't work at all.