I think this is correct....
Open Pour aka "Hand Pour": One piece mold that you hand pour the bait.
Advantages: inexpensive, no injector needed.
Disadvantages: bait has a flat side (for most people!), some find it difficult to pour with out flash/over pour. Very difficult to pour small appendages.
Top Pour aka Top Hand Pour: Two piece mold that you hand pour into the top and gravity and flow fill the mold
Advantages: No injector needed. No runner. 2 sided baits with detail on both sides.Great forSenko type baits. Some molds can use an injector if sprue is modified.
Disadvantages: Slower than injecting. Bait design is limited. One sprue per bait.
Side Injection: Two piece mold that requires an injector. Typically each bait is filled on the side of the bait with no sprue to hold extra plastic. Nose pour side injection is possible with short runner coming off the injection point and curving into the nose of the bait. Typically these molds do not have a very large (if any sprue) due to the need for think aluminum. Most common side injected mold is a skirt mold.
Advantages: slightly cheaper than top injection because you don't have to machine a runner, and uses less aluminum.
Disadvantages: Typically...Cannot do top/bottom laminates but front/back different colors are possible...but look funny! You have to hold pressure with your injector which acts like a sprue/runner to fill for shrinking plastic. Thick aluminum needed to accommodate injector. More expensive due to thicker aluminum and CNC time. Trim mark on side of bait.
Top Injection: Two piece mold that requires injector. Often has a runner to feed multiple cavities.
Advantages: Significantly better options for bait design since pressure on the flow will fill small cavities and extremities. Two sided baits with very good detail and small appendages. Also allows for top/bottom laminates. Runner allows for multiple cavities with one injection. "Easy" top/bottom laminates. Sprue/runner to accommodate for plastic shrinkage (or cause sucking from the head of the bait when they cool first!).
Disadvantages: More expensive due to more aluminium (mold) and CNC machine time. Sprue/runner can cause sucking issues on head of the bait if pressure is not held for proper length of time.
I hope this helps. I'm sure there is some debate on my advantages/disadvantages!