Of all the coating possiblities out there it will be hard to surpass powder painting unless you are going to dip hundreds and thousands of jigs.
The new Mother company here, Do-It, sells the line of liquid dipping paints for jigs but it needs to be thinned to handle well and fluorescent colors need to be undercoated with white. Lure Craft has Poly-Sil which is more in line with epoxy in that it requires you to mix two parts to get your paint. The Poly-Sil will require a base coat for fluorescent colors too. There are some water-based air-brush paints now that get plenty of attention too. You have a ton of options but basically you'll find a bunch of extra handling with anything liquid where powder paint goes on and gets set right in the oven on the drying rack and the colors do not require any undercoating to look nice.
If you do powder paint, by all means get a fluid bed put together and get accustomed to using it. A fluid bed will cut your painting time in half.
Every coating on the market today has its advantages and draw-backs. Most are cheap enough to try for a short time to see if you find advantages over your current method of painting. Head finishes are just like the clothes we buy in that the one-size- fits-all ideal just doesn't cut it. Some will work in certain situations while others might not work at all. Play around and find which works best for you for your own application.
For those that are not aware of this, many of the glitters we use in our plastic tolerate the heat of powder painting and can add a whole new dimension to a head finish.The pearl and hi lite colors we use in plastic will also go into powder paint AND into the paints sold here at Do-It to create some mind bending finishes. Finishes are just basic coverings. Use your imagination to take your head colors a step futher. Remeber, the angler looking at your products judges them pretty harshly. If you have something that isn't an everyday color, some of that scrutiny comes down.