I'm not really sure how big the vents have to be exactly, it depends a lot on the mold. Usually I just scratch out parts (similar ton aluminum mold) with a nail after it's dried for twenty four hours. My guess is the vents won't have to be that big.
Yes you can inject them, but be EXTREMELY careful. I wouldn't recommend doing this at all, however it CAN be done. I've broken several molds when I tried to inject them, but I've never broken a mold just hand pouring it.
On a side note, make sure to seal the mold where the plastic will be at; I believe you can use 1 part of elmers glue to 1 part of water but I've never tried that. I always use mod podge, I think you can get this at walmart if you want to use it.
Josh